Sildenafil 100 mg: what is its effect?

Sildenafil 100 mg is one of the most well-known treatments for erectile dysfunction (ED), a condition that affects millions of men around the world. More than just a medication, it represents an effective solution to help men regain a satisfying sexual life. But how exactly does it work, and how long does its effect last? This article breaks down its mechanism of action, duration of effect, and its implications for users.

The mechanism of action of Sildenafil

Sildenafil, known under the brand name Viagra®, belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. This drug acts directly on the biological mechanisms that regulate erection.

1. The biological basis of erection: When a man is sexually stimulated, his body releases nitric oxide (NO) into the tissues of the penis. This molecule activates an enzyme that produces cyclic guanosine monophosphate (cGMP), responsible for the relaxation of smooth muscles and the increase of blood flow in the penis. This process allows for an erection.
2. The role of PDE5: PDE5 is an enzyme that breaks down cGMP, ending an erection. In some men, excessive PDE5 activity can prevent a sustained erection.
3. How Sildenafil works: Sildenafil inhibits the action of PDE5, allowing cGMP to remain active for a longer period. This prolongs the relaxation of smooth muscles and promotes sufficient blood flow to maintain an erection.

It is essential to note that Sildenafil does not induce a spontaneous erection. Sexual stimulation is necessary for it to work.

The stages of effectiveness

1. Absorption: Sildenafil begins to be absorbed into the bloodstream approximately 30 to 60 minutes after ingestion. To optimize its effect, it is recommended to take it on an empty stomach, as a heavy or fatty meal can delay its absorption.
2. Maximum effect: The effects of Sildenafil are generally at their peak between 1 and 2 hours after ingestion.
3. Duration of effect: A 100 mg dose may remain effective for about 4 to 6 hours, although this duration can vary from one individual to another. Some men report some effectiveness up to 8 hours after taking it.

The duration of Sildenafil's effect: influencing factors

The duration of Sildenafil's effect can vary depending on several factors:

1. Individual metabolism: Each person metabolizes the drug at a different rate. Younger or healthier men may experience longer effects than those with metabolic or liver problems.
2. Nutrition: A heavy or fatty meal can slow down the absorption of the medication, delaying its effect.
3. Dose: The standard dose is 50 mg, but Sildenafil 100 mg is prescribed for more severe cases. A higher dose may prolong the effect, but it can also increase the risk of side effects.
4. General health status: Health issues such as diabetes, heart diseases, or hormonal disorders can affect the effectiveness of Sildenafil.
5. Interactions with other substances: Excessive consumption of alcohol or the use of certain medications can alter the effects of Sildenafil.

How to safely take Sildenafil 100 mg?

1. Medical Prescription: Sildenafil must be prescribed by a doctor after a complete evaluation of your health condition.
2. Respect the dosage: Never exceed the prescribed dose. An overdose can lead to serious complications, such as priapism (prolonged and painful erection).
3. Follow the instructions: Take the medication about an hour before sexual activity.
4. Consult in case of side effects: Side effects may include headaches, facial flushing, visual disturbances, or digestive issues. If these symptoms persist, consult your doctor.

The benefits of Sildenafil

1. Fast and efficient: Its quick action and reasonable duration make it a popular choice.
2. Established reputation: Millions of men around the world have been successfully using Sildenafil since its introduction in 1998.
3. Availability: It is widely available in generic forms, making treatment more accessible.

Sildenafil 100 mg is a recognized treatment for erectile dysfunction, offering an effective and temporary solution to improve the quality of sexual life. Thanks to its targeted mechanism of action and its duration of effect of 4 to 6 hours, it allows men to regain their self-confidence. However, its use must be supervised by a health professional. By consulting a doctor, especially through online platforms like kano.care, you can access a quick medical evaluation and obtain a suitable treatment, safely and discreetly.